Department of Health and Human ServicesIssuing agency·Maryland·via the SAM.gov Get Opportunities APIWe post new science & technology research opportunities in Maryland as agencies publish them. Get them in one email — free, and unsubscribe whenever.
(i) This is a combined synopsis/solicitation for commercial items prepared in accordance with FAR Subpart 12.6, as supplemented with additional information included in this notice. This announcement constitutes only solicitation; proposals are being requested, and a separate written solicitation will not be issued.
(ii) The solicitation number is 75N98026Q00986. This solicitation is issued as a competitive combined synopsis/solicitation for commercial products or commercial services. The Government intends to award a contract or purchase order resulting from this solicitation using full and open competition.
This acquisition is conducted under the authority of FAR 12.603, Streamlined Solicitation for Commercial Products or Commercial Services, and is not expected to exceed the simplified acquisition threshold (if applicable).
The National Institutes of Health (NIH), Office of the Director, Office of Acquisitions, seeks to award a (Firm-Fixed-Price) to the offeror responsible whose proposal represents the best value to the Government.
(iii) The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular effective August 7, 2026
(iv) The associated NAICS code is 325414 Biological Product (except Diagnostic) Manufacturing and the small business size standard is 1250 Employees.
This requirement is unrestricted.
The contractor shall independently furnish all necessary services, qualified personnel, material, equipment, and facilities to conduct a pharmacokinetic (PK/PD) study in mice after IV and PO single dose of a lead NNMT inhibitor (n=3/group). The contractor will monitor plasma PK of parent and 1-MNA at 0, 5, 15, 30 min, 1, 2, 4, 8, 12, 24 hr post dose, and provide concentration vs time curves and PK parameters in an Excel report. Test articles are 3 compounds. Deliverables include blood work results, PK results, and results sent via email to NCATS. Reporting is due within 3 weeks of receipt of compound. NCATS will provide the NNMT inhibitors.
"20201""Washington""DC""US""Hubert H. Humphrey Building 200 Independence Avenue, SW ""20892""Bethesda""MD""US""3100 Center Drive Room 1B59""20892""BETHESDA""MD""USA""6011 EXECUTIVE BLVD., SUITE 503L""Sol_75N98026Q00986.pdf"521597"file"".pdf""1""2026-08-07T23:30:18.646+00:00""c406b87096a146ef8d760f03c3f77dd5""public""0""public""2c5a0a68364a497cb6f0106e6c91cc1c""0"1"0"Source: SAM.gov (notice 25a06a48d8034785ac11d4dbb353048a), retrieved via the SAM.gov Get Opportunities API. View the official posting , always confirm requirements and deadlines with the issuing agency.