Department of Health and Human ServicesIssuing agency·Washington, DC·via the SAM.gov Get Opportunities APISPECTRA will identify and act on autism trajectories, the evolving developmental paths individuals follow across the lifespan from the prenatal period through aging, spanning autism characteristics, co-occurring conditions, and functional outcomes together with the genetic, biological, behavioral, iatrogenic (medical influences), environmental factors and their nonlinear interactions. Rather than examining these factors in isolation, SPECTRA will examine how they combine and interact, including their nonlinear interactions, to produce autism and its co-occurring conditions over time.
SPECTRA will also develop technologies that serve two purposes at once: extending reliable assessment beyond the clinic while improving everyday communication, function, and quality of life. The same tools people use to live more fully will also generate the data that drive measurement and personalized care.
SPECTRA comprises four Technical Areas: TA1 (Multi-Factor Analysis and Trajectory Identification) will identify candidate trajectories from complex interactions among biological, environmental, and developmental factors using existing and novel measures. TA2 (Population-Scale Modeling and Data Integration) will build a federated data network to integrate and harmonize data across institutions at population scale. TA3 (Precision Intervention and Trajectory Testing) will test interventions within trajectories using adaptive platform trials. TA4 (Technologies for Communication, Quality of Life, and Embedded Assessment) will develop technologies such as wearables, communication and speech interfaces, eye tracking, low-channel EEG, and camera-based movement analysis that improve everyday communication and function while generating real-world measurements. The program also includes shared non-solicited resources for data coordination, community engagement and co-design, responsible-use controls, independent evaluation, and transition support.
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"20201""Washington""DC""US""Hubert H. Humphrey Building 200 Independence Avenue, SW ""20892""Bethesda""MD""US""3100 Center Drive Room 1B59""208920004""Bethesda""MD""USA""BG NIHBC 01 Room 228""1 Center Drive""SPECTRA ISO ARPA-H-SOL-26-163.pdf"628341"file"".pdf""1""2026-09-17T16:21:25.42+00:00""2c9618a19adc4c3b96d8e6c692a2de67""public""0""public""4fdca1985d3c4e12a07de2ffa1d6030e""0"2"0""SPECTRA_Attachment A1_TA4 Solution Summary Format and Instructions.pdf"188213"file"".pdf""1""2026-09-17T16:21:25.42+00:00""eac2836ff28943b0a916929af798e5a0""public""0""public""7047a9c97ba44e9d924d7662f49b79e0""0"1"0"Most Washington, DC work asks for the two below, and the solicitation documents are where it’s stated. One prequalification covers both — on this bid and the next.
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Source: SAM.gov (notice ae0ce5edc4c341afbf26a9413cfdae62), retrieved via the SAM.gov Get Opportunities API. View the official posting, and always confirm requirements and deadlines with the issuing agency.